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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFRC
All Species:
1.21
Human Site:
S65
Identified Species:
2.42
UniProt:
P02786
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02786
NP_001121620.1
760
84871
S65
K
P
K
R
C
S
G
S
I
C
Y
G
T
I
A
Chimpanzee
Pan troglodytes
XP_001137174
750
84310
T78
K
K
F
L
Y
N
F
T
Q
I
P
H
L
A
G
Rhesus Macaque
Macaca mulatta
XP_001101316
759
84759
N64
K
P
K
R
C
G
G
N
I
C
Y
G
T
I
A
Dog
Lupus familis
XP_546952
806
88711
A80
L
A
A
T
G
R
R
A
A
P
Y
L
I
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q62351
763
85713
R65
K
P
K
R
F
N
G
R
L
C
F
A
A
I
A
Rat
Rattus norvegicus
Q99376
622
70134
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516658
498
55112
Chicken
Gallus gallus
Q90997
776
85640
R68
Q
P
Q
R
N
G
K
R
L
C
F
L
V
I
A
Frog
Xenopus laevis
NP_001089576
754
85283
K71
E
E
L
L
S
E
M
K
A
E
N
I
R
H
F
Zebra Danio
Brachydanio rerio
NP_001009917
770
84979
Y62
N
Q
R
N
G
Q
Y
Y
P
S
K
L
N
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91406
770
85483
Q69
K
S
D
A
G
V
I
Q
D
N
I
K
T
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M1S8
705
77149
P51
H
P
D
A
V
T
P
P
L
L
F
S
R
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
94.4
41.8
N.A.
76.9
61.9
N.A.
41.4
52.8
24
44.4
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
100
42.3
96.9
57.9
N.A.
87.5
74
N.A.
51.4
69.7
43.2
64.9
N.A.
N.A.
N.A.
38.8
N.A.
P-Site Identity:
100
6.6
86.6
6.6
N.A.
53.3
0
N.A.
0
33.3
0
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
73.3
0
N.A.
0
60
6.6
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
17
0
0
0
9
17
0
0
9
9
9
42
% A
% Cys:
0
0
0
0
17
0
0
0
0
34
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
9
0
0
0
9
0
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
9
0
9
0
9
0
0
0
25
0
0
0
9
% F
% Gly:
0
0
0
0
25
17
25
0
0
0
0
17
0
0
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
0
0
0
0
0
9
0
17
9
9
9
9
34
0
% I
% Lys:
42
9
25
0
0
0
9
9
0
0
9
9
0
0
0
% K
% Leu:
9
0
9
17
0
0
0
0
25
9
0
25
9
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
9
17
0
9
0
9
9
0
9
9
9
% N
% Pro:
0
42
0
0
0
0
9
9
9
9
9
0
0
0
0
% P
% Gln:
9
9
9
0
0
9
0
9
9
0
0
0
0
9
0
% Q
% Arg:
0
0
9
34
0
9
9
17
0
0
0
0
17
0
9
% R
% Ser:
0
9
0
0
9
9
0
9
0
9
0
9
0
0
0
% S
% Thr:
0
0
0
9
0
9
0
9
0
0
0
0
25
0
9
% T
% Val:
0
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
9
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _